New Delhi, Jan 01 (ANI): According to new research, a meal can trigger reward signals in the brain twice- first when the food is ingested and again when the food reaches the stomach. The study was published in the journal Cell Metabolism and highlights how close interactions between the brain and the digestive system are able to reinforce food intake and provide a clue as to why people overeat. Food triggers a feel-good hormone dopamine in the brain. Study was conducted on 12 healthy volunteers. Who received a milkshake or a tasteless solution. Interestingly, the subjects' craving for milkshake was proportionally linked to the amount of dopamine released in the brain. This was first of its kind experiment conducted on humans.